Genetic Disorders That Can Cause Infertility In Females

Infertility depends on various factors, and some cases of infertility are due to certain genetic issues or disorders. Genetics play a crucial role when trying to get pregnant and give birth to a new life. Both parents’ genes are involved in conceiving successfully. However, if any of them have fertility issues, then it can cause difficulty in conceiving. Fertility issues can be treated by the best IVF centre in Punjab. Get yourself examined if you have doubts and want to conceive successfully. 

Several factors, such as hormonal factors, immunological factors, genetic factors, psychological factors, lifestyle factors, surgical intervention, infectious diseases, and drugs, can cause fertility issues. This article focuses on genetics and whether genetics can cause infertility in females. Both men and women can be infertile due to several reasons. Although not all infertility cases are due to inherited genetics, it does affect fertility to some extent. Let us understand which genetic disorder affects fertility in females. 

Females can experience infertility due to various reasons such as hormonal changes, age, PCOS, genetics and more. However, you need to consult the best IVF centre in Bathinda to identify the main cause of infertility. Genetic conditions or disorders that can cause infertility in females are as follows: 

  • Turner Syndrome: It is a condition in which a female has only an X chromosome. In normal cases, females have a pair of X chromosomes (XX), but if the female has Turner syndrome, she is born with only one X chromosome. This can lead to various developmental and physical differences, such as a webbed neck, small stature, and infertility. Hormone therapy, medications, or ART (Assisted Reproductive Technology) techniques, etc., are some treatment solutions for this syndrome. 
  • Fragile X-Associated Primary Ovarian Insufficiency (FXPOI): Females with this condition have reduced function of ovaries. This condition causes irregular periods, infertility, early menopause and a rise in hormones. There is no cure for this condition. However, the best IVF centre in Punjab provides treatments such as hormone therapy, genetic counselling and testing, fertility preservation, etc., that can be recommended to manage the condition by easing the symptoms and managing the condition.  
  • Congenital Adrenal Hyperplasia (CAH): It is a genetic disorder that reduces the production of hormones in the adrenal glands. Children born with this condition have ambiguous genitalia (in girls) and enlarged penis (in boys). Surgery and hormone therapy can be suggested. However, couples with these issues refrain from pregnancy as it has a lower fertility rate, impaired fertility and spontaneous miscarriages. 
  • Structural Abnormalities: These include problems in the uterus shape or fallopian tubes, etc. These issues can be corrected with surgery depending on various factors and the severity of the issue. Consult the best IVF centre in Punjab for timely treatment. Once the issue is addressed, the women can conceive. Consult the doctor for your particular case and know your chances of conceiving successfully. 
  • Chromosome Rearrangement: A balance of chromosomes is necessary for conceiving a normal and healthy child; if the chromosomes are rearranged, altered or moved, it could cause imbalance and various issues. This condition can be in both males and females. When such females try to conceive, it can cause miscarriage, implantation failure, and impaired or birth defects in the child. 

Can Females With Genetic Issues Get Pregnant?

Females can get pregnant if they have genetic issues, but it depends on the type and condition of the issue. It also depends on the severity of the genetic disorder. If the female has structural abnormalities, then it can be addressed with surgery and medications. If this isn’t an option, then doctors may recommend PGT (Preimplantation Genetic Testing), which helps diagnose any chromosomal abnormalities in the embryo. 

Besides this, ART (Assisted Reproductive Technology) techniques such as IVF (In-vitro Fertilisation), ICSI (Intracytoplasmic Sperm Injection), and IUI (Intrauterine Insemination) can also be recommended. The doctor will determine which technique will best suit your condition. If pregnancy may result in child defects or impairments, donor eggs, surrogacy, and other such ART techniques can be considered. 


Different factors and the proper functioning of various organs are necessary to ensure a successful pregnancy. One of the factors is genetics, and it has an important role to play in conceiving and ensuring normal and healthy conception. Genetic disorders such as Structural Abnormalities, Congenital Adrenal Hyperplasia (CAH), Fragile X-Associated Primary Ovarian Insufficiency (FXPOI), Turner Syndrome, and Chromosome Rearrangement cause infertility and problems in conceiving. However, you can get treatment from the best IVF centre in Ludhiana. Depending on your particular case, condition and severity of the issue, treatment plans can be suggested.