Stable-Isotope Labeled Particles for Blood Flow Measurement

With years of experience in the pharmaceutical and life science sectors, CD Bioparticles is excited to announce the launch of its new line of Stable-Isotope Labeled Particles to the scientific community, providing scientists and researchers with a powerful tool for a wide range of applications, including regional organ blood flow measurements and particle deposition studies.

Polystyrene particles are prepared by emulsion and emulsion-free polymerization processes and provide a flexible platform for diagnostic and bioseparation applications. Several methods are available for attaching biological ligands to polystyrene particles, including adsorption onto plain polystyrene particles, covalent attachment to surface functionalized particles, and adsorption of ligands of interest onto particles precoated with binding proteins (e.g., streptavidin, protein A, or protein G).

Polystyrene particles have a wide range of applications in scientific research, diagnostics, electronics, pharmaceuticals, and nanotechnology, including latex agglutination assays, lateral flow detection, purification and separation, ion-exchange, and solid phase immunoassays. To help accelerate research for regional organ blood flow measurements and particle deposition studies, CD Bioparticles now offers a wide range of non-radioactive isotope-labeled polystyrene particles.

Stable isotopes are non-radioactive forms of atoms. Although they do not emit radiation, their unique properties allow them to be used in a wide range of applications. CD Bioparticles stable isotope-labeled microspheres are a cost-effective alternative to radioactive and optical microspheres for measuring regional organ blood flow and particle deposition studies. In addition, the high sensitivity of these particles makes them suitable for general applications as well as for measuring low flow states or low flow organs such as skeletal muscle and skin.

These new particles are 15 µm (standard size for blood flow studies) or 10 µm in diameter and are unaffected by irradiation or half-life, ensuring safety. Supplied in 10 mL and 20 mL vials containing approximately 2.5 million spheres per mL, the particles are suspended in normal saline with Tween 80 and 0.01% Thimerosal. In addition, CD Bioparticles offers 10 different stable isotopes for particle labeling (additional labels available upon request), including Samarium Labeled Polystyrene Particles (15 μm and 10 μm, dyed blackberry), Antimony Labeled Polystyrene Particles (15 μm, dyed violet), and Ytterbium Labeled Polystyrene Particles (15 μm and 10 μm, dyed kiwi).

CD Bioparticles is committed to providing high-quality research tools that drive scientific discovery. The company’s Stable-Isotope Labeled Particles are the latest addition to its extensive portfolio of innovative products available in a variety of sizes and isotopic compositions to suit various experimental requirements. The company will continue to provide exceptional customer support and technical expertise to ensure the successful implementation of these products in research projects.

For more information on how these new particles can enable scientists to conduct studies with greater precision and safety, please visit https://www.cd-bioparticles.com/products/stable-isotope-labeled-particles-325.html.

About CD Bioparticles

CD Bioparticles is a leading manufacturer and supplier of various nanoparticles, microparticles, and coatings for R&D as well as commercialization across different application areas, including in vitro diagnostics, biochemistry, cellular analysis, cell separation, and immunoassay. The company also offers various custom services, including chemical surface-functionalization, fluorescent modification, antibody immobilization, as well as nucleic acid and oligo conjugation to meet client specifications.